Spatial control of active CDC-42 during collective migration of hypodermal cells inCaenorhabditis elegans
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چکیده
منابع مشابه
Spatial control of active CDC-42 during collective migration of hypodermal cells in Caenorhabditis elegans.
Collective epithelial cell migration requires the maintenance of cell-cell junctions while enabling the generation of actin-rich protrusions at the leading edge of migrating cells. Ventral enclosure of Caenorhabditis elegans embryos depends on the collective migration of anterior-positioned leading hypodermal cells towards the ventral midline where they form new junctions with their contralater...
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Cell intercalation is a highly directed cell rearrangement that is essential for animal morphogenesis. As such, intercalation requires orchestration of cell polarity across the plane of the tissue. CDC-42 is a Rho family GTPase with key functions in cell polarity, yet its role during epithelial intercalation has not been established because its roles early in embryogenesis have historically mad...
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ژورنال
عنوان ژورنال: Journal of Molecular Cell Biology
سال: 2015
ISSN: 1674-2788,1759-4685
DOI: 10.1093/jmcb/mjv062